Wonderful news for diabetics! Researchers from the Section of Endocrinology, Diabetes & Metabolism, Department of Medicine at the University of Illinois have discovered a novel cell population from peripheral blood that looks like it is capable of becoming islet cell and produce insulin if in the right place! This novel cell population demonstrated characteristics of islet beta cell progenitors including the expression of beta cell-specific insulin gene transcription factors and prohormone convertases, production of insulin, formation of insulin granules, and the ability to reduce hyperglycemia and migrate into pancreatic islets after transplantation into the diabetic mice.
These findings just published in the Biochemical and Biophysical Research Communications 360 (2007) 205–211 can explain our and other researchers findings that when diabetic ulcers are treated with the patients own peripheral blood stem cells other effects are evident apart from the complete healing of the ulcers, that is IMPROVEMENT of their diabetes. It is very probable that this cell population migrates to the pancreas and restarts insulin production!
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