Wednesday, July 22, 2009

A cure for Type 1 Diabetes - with Peripheral Blood Stem Cells

While researchers battle it out trying to prove the supremacy of various stem cell types (embryonic, mesenchymal etc.), it is worth remembering that so far, blood derived stem cells have been used for a great variety of cures (if you know of any human that has been actually cured with an embryonic stem cell, please let us know).

During my nocturnal, pre-bedtime web surfing (I suspect that I'm not the only one with this habit...), I came across a video describing the way blood stem cells* obtained from the same patient was used to provide a successful treatment for patients with recently diagnosed type 1 diabetes. This work isn't that new -I blogged about it back in 2007- but it is a very significant milestone in the history of stem cell transplantation.

Dr. Richard Burt's work is really quite demonstrative of how our blood and immune system plays a very significant role in whether our tissues and organs break down- and where stem cells obtained non-invasively from the same patient's own blood stream- have a clear role to play. I have yet to meet Dr. Burt in person but know him through his work and this video is the first I've seen of him providing a very clear insight into the trial that he is conducting. He highlights that 14 out of 15 patients were successful in treatment and this is an excellent base number to build on for the next clinical trial.

Dr. Burt published his work in the well renown and respected Journal of American Medical Assocation (JAMA), but instead of reading it I thought this video version sums it up really nicely for the non-medical and patient community.



If watching the video makes you more interested in reading the journal article, click on this link Autologous Nonmyeloablative Hematopoietic Stem Cell Transplantation in Newly Diagnosed Type 1 Diabetes Mellitus.


*StemLife offers individuals the opportunity to bank their babies' cord blood or stem cells from adult blood for therapeutic use.

No comments: