Monday, December 04, 2006
Young Blood. Muscle Repair. Count Dracula links Immortality, Youth & Rapid Healing
I came across this very interesting article describing what some Stanford researchers have been working on earlier this year. In an interesting experiment designed to examine aging and stem cell research, the researchers drew blood from young mice and injected them into genetically identical older mice (imagine storing your young blood and injecting it when you're older).
The result was exciting in that the young blood activated stem cells in the old mice's muscles, allowing them to recover from injury much fast than they used to.
"It's not so much about making people live longer," said Dr. Thomas Rando, associate professor of neurology at Stanford University School of Medicine. "But if some older person gets a broken bone or skin wound, maybe we could improve their recovery rate. Maybe there's a chance to enhance the potential of old tissues."
However, the blood supply was over a lengthy period of six weeks and wasn't as straightforward as a simple blood transfusion. But what the researchers also discovered was that there are "youth-inducing" molecules in the young blood that are responsible for switching on stem cell capabilities in old muscles, which will be the next project. Essentially, injecting stem cells alone may not be the only way to get muscles to repair, and it may be a combination of the right growth factors that also help to get the stem cells to work faster or better.
An excerpt from the article:
Rando and his colleagues studied muscle stem cells called satellite cells, which in young mice and humans induce repair when injury strikes. Rando found in previous work that satellite cells exist in older muscle, but they don't respond to a muscle's cry for help after injury. In the new study, the presence of younger blood helped the satellite cells work more like they do in young mice.
According to Dr. Rando, "Many stem-cell applications in people include diseases of old people," he said. "So if the environment of the heart, brain, liver (and) pancreas is less conducive (to healing) than that of a young person, it would be important to know that in advance."
It was thought that Bram Stoker was writing about patients with the genetic condition porphyria, where they are symptomatically anaemic and have hypersensitive skin, making them averse to sunlight (Vampires burning in sunlight- check out the movie Blade for some very cool effects). In the previous centuries, those with these condition thought that drinking blood of others would ensure their survival, and systematically robbed fresh graves seeking their cure. Now, those diagnosed with this condition congenitally may undergo a stem cell transplant for a cure.
But for immortality, Count Dracula recognized that only the young that provided this elixir (hence pursuing Mina). So was Count Dracula after the young blood or the growth factors in young maidens? I suspect that it was probably both.
Count Dracula Blood Quote on Blood and Immortality:
"Blood... Blood... Life... Years of life."
Count Dracula Blood Quote on Blood as a Food:
"We must survive, all of us. The blood of a human for me, a cooked bird for you. Where is the difference?"
If you'd like to contact Dr. Rando, you can find him here.
If you'd like to contact StemLife about storing your youthful blood, you can contact us at (6012) 2050 165. :)
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